FREMGANGSMAATE FOR FREMSTILLING AV EN VAKSINE MOT VIBRIO ANGUILLARUM.

摘要

Method for making a vaccine against Vibrio anguillarum and other closely related vibrios. Cells containing a virulence plasmid are grown under iron limitation to allow expression of the 86, 000 dalton protein OM2 present in the outer membrane of Vibrio anguillarum when the cells are grown under iron limitation. These cells, or isolated OM2, are then used as a vaccine.