PROCESS FOR OBTAINING 210HYDROXY-20-METHYL-PREGNANE DERIVATIVES

摘要

A steroid of the formula IMAGE in which @ is a single or double bond is manufactured by fermenting at pH 6 to 8 a sterol containing a free hydroxyl group in the 3-position or a corresponding compound containing another oxygen- containing function in the 3- position with a culture of a microorganism selected from Mycobacterium spec. NRRL B-3683 and B-3805 and their variants and mutants, at least a part of the fermentation being carried out in the presence of a boron- containing agent selected from borate ions and organic boron compounds.