Compounds of the formula IMAGE wherein R1-is hydrogen, alkyl of 1 to 6 carbon atoms or benzyl; R2-is alkyl of 1 to 6 carbon atoms, cycloalkyl of 5 to 7 carbon atoms or, together with R1 and the adjacent nitrogen atom, pyrrolidino, piperidino, hexamethyleneimino, morpholino or N'-methyl-piperazino, where each of the heterocycles may have one or two alkyl of 1 to 3 carbon atoms or one or two methoxy substituents attached thereto; R3,-R4 and R5 are each hydrogen or methyl; R6-is alkyl of 1 to 4 carbon atoms; and A-is alkylene of 2 to 4 carbon atoms; AND NON-TOXIC, PHARMACOLOGICALLY ACCEPTABLE ACID ADDITION SALTS THEREOF; THE COMPOUNDS AS WELL AS THEIR SALTS ARE USEFUL AS BRONCHOSPASMOLYTICS AND BRONCHOSECRETOLYTICS.
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机译:式的化合物,其中R 1-为氢,1-6个碳原子的烷基或苄基; R 2-为1至6个碳原子的烷基,5至7个碳原子的环烷基,或与R 1和相邻的氮原子一起,为吡咯烷基,哌啶子基,六亚甲基亚氨基,吗啉代或N'-甲基-哌嗪子基,其中每个杂环可为具有一个或两个具有1至3个碳原子的烷基或一个或两个甲氧基取代基; R3,-R4和R5各自为氢或甲基; R6-为具有1-4个碳原子的烷基; A-为具有2-4个碳原子的亚烷基;及其非毒性,药理学上可接受的酸性添加盐;化合物及其盐可用作支气管溶栓剂和支气管分泌溶酶剂。
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