new 17 - oxazolin - steroidderivat, seen for framstellning derav and anvendning derav at framstellning of corticosteroids

摘要

Novel 17-oxazoline-steroids of the formula IMAGE I wherein R1 is selected from the group consisting of hydrogen, alkyl of 1 to 4 carbon atoms optionally substituted with a member of the group consisting of halogen, oxygen function and nitrogen function and alkenyl and alkynyl of 2 to 4 carbon atoms, R2 is alkyl of 1 to 4 carbon atoms, R3 is selected from the group consisting of hydrogen and hydrocarbon of 1 to 8 carbon atoms and the A,B,C and D rings optionally contain at least one double bond and are optionally substituted with at least one member of the group consisting of -OH, =O, halogen, alkyl and alkoxy of 1 to 4 carbon atoms, and alkenyl and alkynyl of 2 to 4 carbon atoms which are useful intermediates for known steroids having in the 17-position the IMAGE group.