VACCINE FOR ACTIVE IMMUNIZATION CONTAINING HEPATITIS B SURFACE AND/OR E-ANTIGENS

摘要

VACCINE FOR ACTIVE IMMUNIZATIONCONTAINING HEPATITIS B SURFACE AND/OR e-ANTIGENSAbstract of the DisclosureAn antigenic composition, useful as a vaccine orvaccine intermediate, comprising a subparticulate mass, saidmass containing hepatitis B surface and HBe antigens.Disclosed in the application is a process for preparing thesubparticulate composition containing these antigens wherethe particles have a size less than 5 nanometers.