5-DESOXYAPRAMYCIN AND ITS ADDITION SALTS WITH ACIDS, PHARMACEUTICALLY ACCEPTABLE, WITH ACTIVITY AGAINST GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA

摘要

A NEW 5-DESOXYAPRAMYCIN AND ITS ADDITION SALTS WITH ACIDS, PHARMACEUTICALLY ACCEPTABLE, HAVE STRENGTHENED ANTIMICROBIAL ACTIVITY AGAINST GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA, WITH LOWER SIDE EFFECTS, THESE PRODUCTS 5-HYDROXY GROUP OF APRAMYCIN PASSING THROUGH HALOGENATION.