Pharmaceutical compositions containing N-alkyl-N-(nuclearly- substituted) benzylamines having vasotonia-regulating activity

摘要

Aralkylamines of the formula: ##EQU1## wherein R.sup.1 is a phenyl substituted by one of:PP(I) alkyls,P P(II) halo andPP(III) nitro;PPR.sup.2 is PP(IV) alkyl having from 4 to 10 carbon atoms, four of which are in one chain,PP(V) alkyl interrupted by an oxygen atom, i.e. an alkoxyalkyl or ether radical, orPP (VI) hydroxyalkyl wherein the alkyl is either (IV) or (V) and the hydroxy is the sole substituent;PPR.sup.3 is a hydrogen atom, alkyl having from 1 to 4 carbon atoms or such alkyl substituted by a dialkylphosphinyl group;P Pa physiologically-compatible acid-addition salt thereof and a pharmaceutical composition containing such compound(s) as active ingredient(s) are valuable in view of the physiological activity, e.g. vasotonic, capillary sealing and antiarrhythmic, of the aralkylamines and their physiologically-compatible acid-addition salts.