首页> 外国专利> amido substituted benzylamine derivatives of - medicine precursor, their derivatives, their process of preparation and pharmaceutical compositions containing them, and methods of treatment using them.

amido substituted benzylamine derivatives of - medicine precursor, their derivatives, their process of preparation and pharmaceutical compositions containing them, and methods of treatment using them.

机译:药物前体的酰胺基取代的苄胺衍生物,其衍生物,其制备方法和含有它们的药物组合物,以及使用它们的治疗方法。

摘要

This invention encompasses compounds of the formulawhereX1, X2, and X3, independently represent substituents of formula and the pharmaceutically acceptable salts thereof whereinthe remaining variables are as defined herein and wherein said compounds are useful in the diagnosis and treatment of feeding disorders such as obesity and bulimia and cardiovascular diseases such as essential hypertension and congestive heart failure due to the binding of these compounds to human Neuropeptide Y1 receptors.
机译:本发明包括下式的化合物,其中X 1,X 2和X 3独立地表示下式的取代基及其药学上可接受的盐,其中其余变量如本文所定义,并且其中所述化合物可用于诊断和治疗诸如肥胖和贪食症的进食障碍以及由于这些化合物与人Neuropeptide Y1受体结合而引起的心血管疾病,例如原发性高血压和充血性心力衰竭。

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