N-Haloalkyl nor apomorphines and method of inactivating dopamine receptor sites and enhancing dopaminergic activity therewith

摘要

N-substituted haloalkyl apomorphines of the formula ##STR1## wherein R. sub.1 is hydrogen or R.sub.2 O; R.sub.2 is hydrogen, acyl, lower alkyl or ##STR2## R.sub.3 and R.sub.4 are lower alkyl; and X is halogen; and their acid addition salts. Representative compounds have neuroleptic properties.