3-(1-Hydroxyethyl)-4-(but-2-ene)-azetidin-2-one and derivatives

摘要

Disclosed is a process for the total synthesis of thienamycin from substituted 4-allylazetidinone (IIIa) via intermediate III: ##STR1## wherein: R=H, blocking group or a salt cation; and R° is alkyl, aralkyl, cycloalkyl, or cycloalkylalkyl.