PREPARATION OF AQUEOUS SOLUTION OF 3-CHLORO-2- OXYPROPYLTRIMETHYLAMMONIUM CHLORIDE

摘要

PURPOSE:To obtain the titled compound useful as an agent for making cellulose, etc. cationic, etc. in high yield, by mixing continuously equimolar amounts of an aqueous solution of trimethylamine hydrochloride and epichlorohydrin at a specific temperature successively. CONSTITUTION:Equimolar amounts of an aqueous solution of trimethylamine hydrochloride shown by the formula I and epichlorohydrin shown by the formula II are mixed continuously with keeping the reaction temperature at =70 deg.C, to give an aqueous solution of 3-chloro-2- oxypropyltrimethylammonium chloride shown by the formula III. When the reaction is carried out by adding dropwise the compound shown by the formula II to the compound shown by the formula I , by-products shown by the formulas IV-VI are prepared as a molar ratio of the compound shown by the formula II/the compound shown by the formula I approaches 1, the yield of the desired compound shown by the formula III is reduced and the formation of alpha- dichlorohydrin shown by the formula IV as a by-product is increased. By mixing continuously the equimolar amounts of the compound shown by the formula I and the compound shown by the formula II and carrying out the reaction at =70 deg.C with suppressing heat generation, the formation of the compounds shown by the formulas V and VI as the by-products will not occur, and the formation ratio of the compound shown by the formula III as the by-product is reduced.