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process for preparation of apovincaminiques acid esters and pharmaceutical compositions thus obtained, esters prepared with these esters
process for preparation of apovincaminiques acid esters and pharmaceutical compositions thus obtained, esters prepared with these esters
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机译:载载载脂蛋白树酯的制备方法和由此获得的药物组合物,用这些酯制备的酯
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摘要
A process is disclosed for the preparation of racemic cis or trans apovincaminic acid esters of the formula (I) IMAGE (I) and the corresponding optically active derivatives of the formulae (Ia) IMAGE (Ia) and/or (Ib) IMAGE (Ib) and/or (Ic) IMAGE (Ic) and/or (Id) IMAGE (Id) wherein R1 and R2 are identical or different alkyl groups having 1 to 6 carbon atoms. Apovincaminic acid alkyl esters are well-known vasodilating compounds.
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