首页> 外国专利> Cytostatic alkaloid derivs. from Chelidonium majus L. - intravenously injected for diagnosis and treatment of tumorous cell diseases

Cytostatic alkaloid derivs. from Chelidonium majus L. - intravenously injected for diagnosis and treatment of tumorous cell diseases

机译:细胞静止生物碱的衍生。来自白屈菜(Chelidonium majus L.)-静脉注射以诊断和治疗肿瘤细胞疾病

摘要

Treating a human patient having tumour cells located in the rectum, liver, pancras, stomach, skin, glands, lymphatic system, bone, parotid gland, ovaries, uterus, lungs, prostate, thyroid, abdomen or colon comprises administering a mixt. of non-toxic cytostatic alkaloid derivs. (I) in an amt. of 0.5-650 mg, where at least a portion of (I) is comprised of derivs. of chelilutin so as to at least retard the growth of the tumour cells. The alkaloid derivs. may be formed from an alkaloi extract of Chelidonium majus L.. The chelilutin deriv. may be a chelilutin thiophosphoric acid amide salt where the thiophosphoric acid is selected from thiophosphoric acid triaziridide, thiophosphoric acid-tri(N- sanguinarinol)ethylamine, thiophosphoric acid-di (ethyleneimido) -N-herberinol-ethylamide and N,N',N''-triethylene-thiophosphoramide.
机译:治疗具有位于直肠,肝脏,胰腺,胃,皮肤,腺,淋巴系统,骨骼,腮腺,卵巢,子宫,肺,前列腺,甲状腺,腹部或结肠中的肿瘤细胞的人类患者,包括施用混合液。无毒的细胞抑制生物碱衍生物。 (I)在amt中。 0.5-650mg,其中(I)的至少一部分由衍生物组成。至少要抑制肿瘤细胞的生长。生物碱衍生。可以由白屈菜(Chelidonium majus L.)的碱提取物形成。可以是氯柳丁硫代磷酸酰胺盐,其中硫代磷酸选自硫代磷酸三叠氮化物,硫代磷酸三(N-血红素萘)乙胺,硫代磷酸二(亚乙基亚氨基)-N-小her碱-乙基酰胺和N,N',N -三亚乙基-硫代磷酰胺。

著录项

  • 公开/公告号PT75226A

    专利类型

  • 公开/公告日1983-05-25

    原文格式PDF

  • 申请/专利权人 WASSYL NOWICKY;

    申请/专利号PT19820075226

  • 发明设计人

    申请日1982-07-12

  • 分类号A61K;

  • 国家 PT

  • 入库时间 2022-08-22 11:01:48

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