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Process for the manufacture of derivatives of 2 substitui- two phenylthiazole.

机译:制备2个取代基-两个苯基噻唑的衍生物的方法。

摘要

Known agents for treating peptic ulcers are either not sufficiently effective or possess undesirable side effects. These problems can be overcome by 2-(substituted-phenyl)-thiazoles having the formula (I): …CHEM… wherein R1 represents an alkyl group of 1 to 3 carbon atoms, R2 represents a hydrogen atom or an alkyl group of 1 to 3 carbon atoms and n denotes an integer of 1 to 3, with the proviso that when R2 represents a hyrogen atom the 3-, 4- and 5-positions of the benzene ring are not simultaneously occupied by methoxy groups. These compounds can be formulated into pharmaceutical compositions for treating peptic ulcers.
机译:已知的用于治疗消化性溃疡的药剂不是足够有效或具有不良副作用。这些问题可以通过具有式(I)的2-(取代的苯基)-噻唑来解决:……,其中R 1代表具有1-3个碳原子的烷基,R 2代表氢原子或1-3个碳原子的烷基,n表示1-3的整数,条件是当R 2表示氢原子时,苯环的3-,4-和5-位不同时被甲氧基占据。可以将这些化合物配制成用于治疗消化性溃疡的药物组合物。

著录项

  • 公开/公告号ES507001A0

    专利类型

  • 公开/公告日1983-02-01

    原文格式PDF

  • 申请/专利权人 JUREHA KAGAKU KOGYO KABUSHIKI KAISHA;

    申请/专利号ES19810507001

  • 发明设计人

    申请日1981-10-20

  • 分类号C07D277/56;A61K31/425;

  • 国家 ES

  • 入库时间 2022-08-22 10:47:54

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