A process for the preparation of novel tetrahydroisoquinoline (tetrahydroisoquinoline).

摘要

Novel tetrahydroisoquinoline compounds of the formula: CHEM wherein R1 is lower alkyl or phenyl-lower alkyl, R2 is alkyl or phenyl-lower alkyl, R3 is hydrogen or lower alkyl and R4 is hydrogen, lower alkyl or aralkyl, and pharmaceutically acceptable salts thereof are disclosed. Said compounds (I) and salts thereof are useful as hypotensive agent. There is also described a process for preparation of said compounds as well as pharmaceutical compositions containing same.