Process for the preparation of monoamine oxidase inhibitors.

摘要

Compounds of the formula: CHEM wherein: X is fluorine, chlorine, or bromine, and R is a group of the formula: CHEM wherein R3 is hydrogen, (C1-C4)alkyl, or (C1-C4)alkoxy, and R4 is (C1-C4)alkyl or (C1-C4)alkoxy; or a (C1-C8)alkyl ester thereof; or a non-toxic pharmaceutically acceptable salt thereof; inhibit MAO in vivo and can be administered either alone or in combination with an aromatic L-amino acid decarboxylase inhibitor for the treatment of depression.