A process for the preparation of cicloalca (4,5) pirrolo (2.3 g) - isoquinolinas

摘要

A process for the preparation of cicloalca / 4.5 / pirrolo / 2.3 g / isoquinolinas. They REACT with a compound of General formula (ii) with Phosphorus pentasulphide.The Compound (i) is obtained, which optionally may refer to the following: (a) to End a relationship isomerizar mixture comprising predominantly isomer after being able to separate the Trans isomer in the mixture. (b) resolution of a racemic mixture obtained in the optical Antipodes.(c) convert the compound obtained in the acid Addition Salt of a pharmaceutically acceptable salt in the respective pharmaceutically acceptable.R is Hydrogen, alkyl or aralquilo; R is Hydrogen, alkyl, aralquilo Cycle, alquenilo alkoxyalkyl esters, alkyl, alkyl, alkyl alquinilo, Thienyl, furil aralquenilo, alkyl, or aryl alqueniloxialquilo, ariloxialquilo, N - imidazolinialquilo; n is 3, 4, 5 or 6.