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'A process for the preparation of cicloalca 4.5 pirrolo 2.3 - G - isoquinolinas' as divisional Invention Patent 499.861 N 27 - 2 - 81.
'A process for the preparation of cicloalca 4.5 pirrolo 2.3 - G - isoquinolinas' as divisional Invention Patent 499.861 N 27 - 2 - 81.
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机译:作为分立的发明专利499.861 N 27-2-81的“制备环丙沙醛4.5吡咯啉酮2.3-G-异喹啉类的方法”。
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摘要
A process for the preparation of cicloalca 014 015 4.5 pirrolo 014 015 - G 2.3 - isoquinolinas. The Compound is reacted with formaldehyde (ii). If you want to be isomerized the mixture of isomers obtained (i) until a final relationship involving predominantly the Trans isomer which can be separated from the mixture.The racemic mixture can also be obtained in the optical antipodes, or obtains the pharmaceutically acceptable acid Addition Salt. R is alkyl, cicloalquil alkoxyalkyl Esters or alkyl; n is 3, 4, 5 or 6.
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