A process for the preparation of a water soluble Salt of lysine or arginine dioxide 1.1 - N - (2 - pyridyl) - 2 - methyl - 4 - hydroxy - 3 - benzotiazin 2H - 1.2 - carboxamide.

摘要

Process for the production of a water soluble Salt of lysine or arginine dioxide 1.1 - N - (2 - pyridyl) - 2 - methyl - 4 - hydroxy - 3 - benzotiazin 2H - 1.2 - carboxamide. Involves the reaction of dioxide 1.1 - N - (2 - pyridyl) - 2 - methyl - 4 - hydroxy - 3 - benzotiazin 2H - 1.2 - carboxamide with lysine or arginine.The reaction is used in at least one quantity Association of lysine or arginine and takes place in a protico polar Solvent, such as water or a Lower alcohol, at a temperature between 20 C and 100 C. pharmacological applications as these compounds have antiarthritic agents.