antibiotic bn - 200 and methods for its manufacture

摘要

NEW MATERIAL:Antibiotic substance BN-200 [elemental analysis; C 67.46%, H 7.24%, N 7.55%, O 17.75%: molecular weight 520: Melting point 156 deg.C (decompose): color reactions; positive to ferric chloride reaction; negative to Sakaguchi, biuret, Molisch, and anthrone reactions.]. USE:Antibiotic effective to Gram-positive and Gram-negative bacteria. PROCESS:The objective substance can be separated from culturing medium prepared by the aerobical culturing of BN-200-producing bacteria belonging to Erwinia genus, e.g. Erwinia sp-BN-200 (FERM-P No.3561).