Tablets for the administration of substances drug and method for the manufacture of such tablets

摘要

A pharmaceutical tablet composition for oral administration is disclosed which provides for accelerated release of a finely divided active ingredient contained therein which is only slightly soluble in the gastrointestinal tract of a warm-blooded animal . The tablet composition is characterized as containing a micro-dispersed, amorphous, porous silica having a primary particle size of between about 1 and 15 mu m, a BET surface of between about 350 and 450 m2/g, and a pore volume of between about 1.4 and 1.7 ml/g. A method of producing the tablet composition is also disclosed.