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Paris comprime secable allowing a release, 27 and delayed of the active substance

机译:巴黎妥协安全,允许释放活性物质27

摘要

Divisible tablet having controlled and delayed release of the active substance and consisting of a compact that is optionally provided with a coating and is formed by at least one active substance in an adjunct composition that effects a delayed and controlled release of the active substance and optionally one or more additional adjunct compositions that optionally contain active substances and are arranged in longitudinal layers, the compact being of an oblong shape in which the ratio of length to width to depth is approximately 2.5 to 5: approximately 0.9 to 2:1 and the width constitutes at most 2/3 of the length, and in which one or more relatively deep dividing grooves are present which run perpendicularly to the length and the depth and have a total depth constituting from approximately 1/3 to approximately 1/2 of the depth of the tablet, but are at least so deep that one fracture surface area multiplied by the number of possible fragments constitutes a maximum of 15% of the surface area of the undivided tablet, the base and top faces independently of one another are planar or are convexly curved about the longitudinal axis or about parallels to this axis, the side faces are planar, the end faces can be of any shape and edges are optionally bevelled or rounded.
机译:具有活性物质的控制和延迟释放的可分开的片剂,其由压块构成,该压块任选地具有涂层,并且由至少一种活性物质在辅助组合物中形成,该组合物实现了活性物质和任选的一种延迟和控制释放或更多种附加的附加组合物,它们任选地包含活性物质并排列在纵向层中,该压块为长方形,其中长宽宽比约为2.5至5:大约0.9至2:1,并且宽度构成最多为长度的2/3,并且其中存在一个或多个相对较深的分隔槽,该分隔槽垂直于长度和深度延伸,并且总深度占深度的大约1/3至大约1/2平板电脑,但至少要深到一块骨折的表面积乘以可能的碎片数量就可以构成最多15%的表面在未分割药片的面积上,底面和顶面彼此独立,是平坦的,或者围绕纵轴或平行于此轴呈凸形弯曲,侧面是平坦的,端面可以是任何形状,边缘可以是可选倒角或倒圆角。

著录项

  • 公开/公告号FR2462908B1

    专利类型

  • 公开/公告日1983-07-08

    原文格式PDF

  • 申请/专利权人 CIBA GEIGY AG;

    申请/专利号FR19800017858

  • 发明设计人

    申请日1980-08-13

  • 分类号A61K9/44;

  • 国家 FR

  • 入库时间 2022-08-22 10:01:31

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