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Method of purification of particles of biological origin, in particular of the virus surface antigen of hepatitis b (hbsag) and the products obtained
Method of purification of particles of biological origin, in particular of the virus surface antigen of hepatitis b (hbsag) and the products obtained
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机译:纯化生物学来源的颗粒的方法,尤其是乙型肝炎病毒表面抗原(hbsag)及其获得的产物
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摘要
The invention relates to a process for purifying biological particles, particularly for purifying the surface antigen (HBs) of the hepatitis B virus. A suspension of this HBs antigen is subjected to rate zonal banding in a gradient inside a centrifuge equipped with a continuous-flow core. At the same time as the centrifugation operation is carried out, the suspension of particles to be purified is caused to circulate in a closed circuit in which the centrifuge is inserted. The band containing the purified biological particles is then collected in a way known per se.
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