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GYNOSAPONINS

机译:绞股蓝皂甙

摘要

NEW MATERIAL:A compound shown by the formula [R1 is H; R2 is beta-D-glucopyranosyl, beta-D-xylopyranosyl(1 6)-beta-D-glucopyranosyl, alpha-L-rhamnopyranosyl (1 6)-beta-D-glucopyranosyl; R3 is H, or OH]. EXAMPLE:20S-Protopanaxadiol-3-O-{[ beta-D-glucopyranosyl( 1 2 )-alpha-L-rhamnopyranosyl(1 6) ]-beta-D-glucopyranoside }-20-O-[ beta-D-glucopyranosyl(1 6)-beta-D-glucopyranoside]. USE:An inhibitor for lipid decomposition and an inhibitor for lipid synthesis. PROCESS:Gynostemma pentaphyllum Makino is extracted with water or a water- containing lower alcohol, the alcohol is optionally removed, it is treated with a nonionic absorbing resin. The absorbed saponin is eluted with a lower alcohol, treated with alumina, eluted with the (water-containing) lower alcohol, concentrated, to give crude saponins, which are separated and purified.
机译:新材料:式[R 1]所示的化合物为H; R 2为β-D-吡喃葡萄糖基,β-D-吡喃吡喃糖基(1 6)-β-D-吡喃葡萄糖基,α-L-鼠李糖基吡喃糖基(1 6)-β-D-吡喃葡萄糖基。 R 3为H或OH]。实例:20S-原人参二醇-3-O-{[β-D-吡喃葡糖基(1 6)-α-L-鼠李糖吡喃糖基(1 6)]-β-D-吡喃葡糖苷} -20-O- [β-D-吡喃葡糖基(1 6)-β-D-吡喃葡萄糖苷]。用途:脂质分解抑制剂和脂质合成抑制剂。工艺:绞股蓝(Gynostemma pentaphyllum Makino)用水或含水的低级醇提取,可选择性除去醇,然后用非离子吸收性树脂处理。吸收的皂苷用低级醇洗脱,用氧化铝处理,用(含水的)低级醇洗脱,浓缩,得到粗皂苷,将其分离并纯化。

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