首页> 外国专利> THIAPROSTANSYREDERIVATER FOR USE AS LUTEOLYTIKA FOR HEALTHY MAMMALS AND luteolytic effective PREPARATION FOR HEALTHY MAMMALS

THIAPROSTANSYREDERIVATER FOR USE AS LUTEOLYTIKA FOR HEALTHY MAMMALS AND luteolytic effective PREPARATION FOR HEALTHY MAMMALS

机译:用作健康哺乳动物的脂多糖的硫代前体缩醛剂和对健康哺乳动物的黄体溶解有效制备

摘要

13-Thiaprostanoic acid derivatives of the formula IMAGE wherein A is -CO- or -CHOH-, B is -CH2-CH2- or -CH=CH-, R1 is H or alkyl of 1 to 4 carbon atoms, m is a whole number from 0 to 5, n is a whole number from 0 to 3 or, when B is -CH=CH-, additionally 4, 5, 6, 7, 8 or 9, R2 is alkoxy of 1 to 4 carbon atoms, phenoxy, pyridyl, thienyl, naphthyl, phenyl substituted by F, Cl, Br, OH, OCH3 or OF3 or phenoxy substituted by F, Cl, Br, OH, OCH3, CH3 or CF3 or, when B is -CH=CH-, additionally hydrogen, phenyl or tolyl, R3 is H, methyl or ethyl, possess pharmacological activity, including blood pressure lowering activity.
机译:的13-硫杂锡酸衍生物,其中A为-CO-或-CHOH-,B为-CH2-CH2-或-CH = CH-,R1为H或1-4个碳原子的烷基,m为0到5的整数,n是0到3的整数,或者,当B是-CH = CH-时,另外4、5、6、7、8或9,R 2是1-4个碳原子的烷氧基,苯氧基,吡啶基,噻吩基,萘基,被F,Cl,Br,OH,OCH3或OF3取代的苯基或被F,Cl,Br,OH,OCH3,CH3或CF3取代的苯氧基或当B为-CH = CH-时,另外,氢,苯基或甲苯基,R 3是H,甲基或乙基,具有药理活性,包括降血压活性。

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