A novel ester of the 1-methyl-5-p-toluoylpyrrolyl-2-acetic acid having antiinflammatory, mucolytic and antitussive properties, process for its preparation and pharmaceutical compositions containing them.

摘要

1-methyl-5-p-toluoylpyrrole-2-acetic acid guaiacyl ester, which possesses antiinflammatory, antipyretic, mucolytic and antitussive properties, is disclosed. This ester is prepared by reacting guaiacol with an activated derivative of the 1-methyl-5-p-toluoylpyrrole-2-acetic acid of formula IMAGE wherein X is an activating group suitable for promoting the formation of an ester bond.