首页> 外国专利> PROCESS FOR PREPARING (1,5) 6,6-DIMETHYL 5-HYDROXY 3-OXA BICYCLO /3.1.0./ HEXAN-2-ONE AND ANY 4-ETHER STEREOISOMER THEREOF

PROCESS FOR PREPARING (1,5) 6,6-DIMETHYL 5-HYDROXY 3-OXA BICYCLO /3.1.0./ HEXAN-2-ONE AND ANY 4-ETHER STEREOISOMER THEREOF

机译:制备(1,5)6,6-二甲基5-羟基3-氧杂双环/3.1.0./己二-2-酮及其任何4-醚立体异构体的方法

摘要

ABSTRACT OF THE DISCLOSURE: The invention relates to a method for preparing the compounds (1RS, 4RS, 5RS), (1R, 4R, 5S) or (1S, 4S, 5R) of formula I: (I) where Y is hydrogen or the residue Z of an alcohol ZOH possible chiral-ment. This method consists in reacting in the presence of an acidic agent, the compound II: (5RS) either with a compound ZOH achiral, reacting the ether obtained with III: wherein R1 and R2 are aromatic groups which may be substituted, of isopropyl or tertiary alkyls, for I where Y = Z, and hydrolyzing, if desired, either with a compound ZOH chiral optically active separating stéréoisimères ethers formed, reacting them with III and hydrolyzing, if desired, the compounds I thus obtained. The compounds I are intermediates in the preparation of cyclopropane carboxylic acids, acid esters lead to insecticides.
机译:发明内容本发明涉及一种制备式I的化合物(1RS,4RS,5RS),(1R,4R,5S)或(1S,4S,5R)的方法:(I)其中Y是氢或醇ZOH的残基Z可能是手性的。该方法在于在酸性试剂存在下,使化合物II:(5RS)与化合物ZOH非手性化合物反应,使所获得的醚与III:其中R 1和R 2为异丙基或叔取代基的芳族基团反应。烷基,对于I,其中Y = Z,并且如果需要,可以用化合物ZOH手性旋光活性分离形成的立体醚进行水解,使它们与III反应,并且如果需要,可以水解得到的化合物I。化合物Ⅰ是制备环丙烷羧酸的中间体,酸酯导致杀虫剂。

著录项

  • 公开/公告号CA1176645A

    专利类型

  • 公开/公告日1984-10-23

    原文格式PDF

  • 申请/专利权人 ROUSSEL-UCLAF;

    申请/专利号CA19800357376

  • 申请日1980-07-30

  • 分类号C07D307/93;

  • 国家 CA

  • 入库时间 2022-08-22 09:03:35

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