(−)-N,N′-Bis[(1S,2R,5S)-6,6-dimethyl-bicyclo­[3.1.1]heptan-2-ylmeth­yl]pyridine-2,6-dicarboxamide monohydrate

摘要

The title compound, C27H39N3O2·H2O, is a chiral pyridine-2,6-dicarboxamide derivative including cis-myrtanyl groups as amine substituents. The pyridine-2,6-dicarboxamide core approximates C 2 point symmetry and a solvent water mol­ecule lies on the pseudo-twofold axis. The water mol­ecule serves both as acceptor and donor for efficient hydrogen bonds involving N—H and C=O functional groups as donor and acceptor groups, respectively. As a result, each water mol­ecule in the crystal structure is tetra­hedrally bonded to three symmetry-related mol­ecules, forming a three-dimensional supra­molecular network. Such an arrangement is a common feature found in the majority of X-ray-characterized sym­metrically substituted pyridine-2,6-dicarboxamide derivatives.