wherein R, is hydrogen, -C02R4, R4; R2 is hydrogen,R4 is alkyl of 1 to 4 carbon atoms, R5 is alkyl of 1 to 8 carbon atoms; X is halogen, alkyl of 1 to 4 carbon atoms, alkoxy of 1 to 4 carbon atoms, CF3, and OH; m is an integer of 0, or 2; and n is an integer of 1 or 2, and a process for their preparation. The compounds can be used as analgesics."/>
Substituted 1-azaspiro(4.5)decanes and 1-azaspiro(5.5)-undecanes, intermediates and a process for their preparation, and their use as medicaments
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Substituted 1-azaspiro(4.5)decanes and 1-azaspiro(5.5)-undecanes, intermediates and a process for their preparation, and their use as medicaments
Substituted 1-azaspiro(4.5)decanes and 1-azaspiro(5.5)-undecanes, intermediates and a process for their preparation, and their use as medicaments
The present invention relates to substituted 1-Azaspiro [4.5] decanes and 1-Azaspiro [5.5] undecanes of the general formulawherein R, is hydrogen, -C02R4, R4; R2 is hydrogen,R4 is alkyl of 1 to 4 carbon atoms, R5 is alkyl of 1 to 8 carbon atoms; X is halogen, alkyl of 1 to 4 carbon atoms, alkoxy of 1 to 4 carbon atoms, CF3, and OH; m is an integer of 0, or 2; and n is an integer of 1 or 2, and a process for their preparation. The compounds can be used as analgesics.
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机译：本发明涉及通式的取代的1-氮杂螺[4.5]癸烷和1-氮杂螺[5.5]十一烷 <图像文件=“ IMGA0001.GIF” he =“ 33” imgContent =“ chem” imgFormat =“ GIF” inline =“ no” wi =“ 54” /> 其中R ，是氢，-C0 2 R 4 ，R 4 ; R 2 是氢， <图像文件=“ IMGA0002.GIF” he =“ 19” imgContent =“ chem” imgFormat =“ GIF” inline =“ no” wi =“ 81” /> <化学id =“ chema03”> <图像文件=“ IMGA0003.GIF” he =“ 17” imgContent =“ chem” imgFormat =“ GIF” inline =“ no” wi =“ 43” /> R 4 是具有1至4个碳原子的烷基，R 5 是具有1至8个碳原子的烷基; X是卤素，1-4个碳原子的烷基，1-4个碳原子的烷氧基，CF 3 和OH; m是0或2的整数; n是1或2的整数，及其制备过程。该化合物可用作镇痛药。
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