SUBSTITUTED 1-AZASPIRO(4.5)DECANES AND 1-AZASPIRO(5.5)-UNDECANES, INTERMEDIATES AND A PROCESS FOR THEIR PREPARATION, AND THEIR USE AS MEDICAMENTS

摘要

The present invention relates to substituted 1-Azaspiro [4.5] decanes and 1-Azaspiro [5.5] undecanes of the general formula …CHEM… wherein R1 is hydrogen, -CO2R4, R4; R2 is hydrogen, …CHEM… R4 is alkyl of 1 to 4 carbon atoms, R5 is alkyl of 1 to 8 carbon atoms; X is halogen, alkyl of 1 to 4 carbon atoms, alkoxy of 1 to 4 carbon atoms, CF3, and OH; m is an integer of 0, 1 or 2; and n is an integer of 1 or 2, and a process for their preparation. The compounds can be used as analgesics.