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Fraction extracted from bone marrow, which is soluble in water which is capable of reguler the host immune reactions of a screw - to - screw of the cells or of a fabric allogenic, compositions containing this fraction and to the to prepare
Fraction extracted from bone marrow, which is soluble in water which is capable of reguler the host immune reactions of a screw - to - screw of the cells or of a fabric allogenic, compositions containing this fraction and to the to prepare
PCT No. PCT/EP80/00136 Sec. 371 Date Jul. 2, 1981 Sec. 102(e) Date Jul. 2, 1981 PCT Filed Nov. 21, 1980 PCT Pub. No. WO81/01367 PCT Pub. Date May 28, 1981.Water soluble biologically active fraction obtainable from the physiologically inter-cellular medium bone-marrow and process for preparing said fraction and the pharmaceutical compositions containing said fraction. The characteristics are notably the following: it is substantially free of the inhibitors having molecular weights lower than 30,000; it is lyophilizable without loss of biological properties; it exhibits the biological activities in the form of a solution having a pH of at least 7; it stimulates H-thymidin incorporation by bone-marrow cells in vitro and in vivo; the water soluble fraction is capable of controlling the immune reactions of a host against allogenic cells or tissue.
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