首页>
外国专利>
New derivatives osteoblasts 17 (20), their process of preparation and their application for the preparation of corticosteroids
New derivatives osteoblasts 17 (20), their process of preparation and their application for the preparation of corticosteroids
展开▼
机译:新衍生物成骨细胞17(20),其制备方法及其在糖皮质激素制备中的应用
展开▼
页面导航
摘要
著录项
相似文献
摘要
A novel nitromethylation composition comprising nitromethane and a catalytic amount of a bifunctional basic catalyst, optionally in an organic solvent, a method of nitromethylating ketonic compounds with said compositions and novel steroids of the formulae IMAGE I and IMAGE I' wherein R1 is selected from the group consisting of hydrogen, alkyl of 1 to 4 carbon atoms optionally substituted with an oxygen or nitrogen group or halogen and alkenyl and alkynyl of 2 to 4 carbon atoms, R2 is alkyl of 1 to 4 carbon atoms and the A,B,C and D rings optionally contain at least one double bond and optionally substituted with at least one member of the group consisting of -OH, =0, halogen, alkyl and alkoxy of 1 to 4 carbon atoms and alkenyl and alkynyl of 2 to 4 carbon atoms and their use to form the corresponding 21-acetoxy-20-ketocorticosteroids compounds in a simple manner.
展开▼