Obtaining mutants of clostridium acetobutylicum a high suitable of butanol and acetone, mutant obtained and the use of these mutants for the production of butanol and acetone

摘要

The Clostridium acetobutylicum mutant IFP 904 (ATCC 39058) is obtained by spreading a culture of a strain of Clostridium acetobutylicum at the surface of a solid culture medium containing n-butanol at a specified concentration, growing the strain in the presence of a mutagenic agent and recovering a strain of increased resistance to n-butanol. The resultant mutant can be used to produce a mixture of butanol and acetone of increased concentration.