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the use of ibogaine in the manufacture of a medicament for the treatment of narcotic misbrugssyndrom

机译:依博加因在制造用于治疗麻醉性误疹的药物中的用途

摘要

The administration to a heroin addict of ibogaine, ibogaine HCl or other non toxic salts of ibogaine, an alkaloid of the family apocynaceae, has been discovered to unexpectedly interrupt the physiological and psychological aspects of the opiate addiction syndrome. A single treatment was effective for about 6 months, and a series of 4 treatments was effective for approximately 3 years. The treatments consisted of the oral administration of ibogaine or its salts in dosage ranges of 6 mg/kg to 19 mg/kg. The minimum effective dose was 400 mgs and dosage increases above 1000 mgs were found to be unnecessary. Treatments were effective in 71% of the cases.
机译:已发现对海洛因成瘾者依博加因,盐酸依博加因盐酸盐或依博加因的其他无毒盐(鸦片藻科的一种生物碱)进行给药会意外地中断阿片成瘾综合症的生理和心理方面。单一治疗有效期约为6个月,而一系列4种治疗有效期约为3年。治疗包括口服剂量为6 mg / kg至19 mg / kg的伊博加因或其盐。最小有效剂量为400毫克,发现没有必要将剂量增加到1000毫克以上。在71%的病例中治疗有效。

著录项

  • 公开/公告号DK316485D0

    专利类型

  • 公开/公告日1985-07-11

    原文格式PDF

  • 申请/专利权人 LOTSOF HOWARD S.;

    申请/专利号DK19850003164

  • 发明设计人 LOTSOF HOWARD S.;

    申请日1985-07-11

  • 分类号C07D;A61K;

  • 国家 DK

  • 入库时间 2022-08-22 08:17:06

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