首页>
外国专利>
FOERFARANDE Foer FRAMSTAELLNING AV NYA TERAPEUTISKT ANVAENDBARA TRIPEPTIDER
FOERFARANDE Foer FRAMSTAELLNING AV NYA TERAPEUTISKT ANVAENDBARA TRIPEPTIDER
展开▼
机译:制备新的可治疗的三联疗法的程序
展开▼
页面导航
摘要
著录项
相似文献
摘要
There are disclosed new biological active polypeptides: A-X-B wherein A is deamino-LYS or LYS; X is a suitable neutral aliphatic amino acid residue; e.g., one selected from the group consisting of SER, ALA, 2-Me-ALA, GLY, LEU, THR, D-SER, D-ALA, D-THR, allo-THR, D-LEU, and SAR; B is GLN-R', decarboxy-GLN, or IMAGE and R' is a substituent which does not substantially affect the biological activity of the tripeptide. These polypeptides have the capability of inducing the differentiation of T-lymphocytes as measured by the acquisition of the thymic differentiation antigen Th-1, as well as B-lymphocytes as measured by the acquisition of the differentiation antigen Bu-1. The polypeptides are thus useful in thymic function and immunity areas such as in treatment for congenital absence of thymus. Also provided are therapeutic compositions and methods for use of the polypeptides.
展开▼