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MIXED SALTS OF ESSENTIAL OR SEMI-ESSENTIAL AMINO ACIDS AND NITROGEN-FREE ANALOGUES THEREOF AND THEIR USE IN THE TREATMENT OF RENAL AND HEPATIC DISORDERS
MIXED SALTS OF ESSENTIAL OR SEMI-ESSENTIAL AMINO ACIDS AND NITROGEN-FREE ANALOGUES THEREOF AND THEIR USE IN THE TREATMENT OF RENAL AND HEPATIC DISORDERS
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机译:基本或半基本氨基酸和无氮类似物的混合盐及其在治疗肾脏和肝脏疾病中的用途
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摘要
Novel compounds are prepared by reacting essential or semi-essential amino acids with nitrogen-free analogues thereof, particularly alpha-keto and/or alpha-hydroxy analogues. The mixed salt reaction products are precursors of essential and semi-essential amino acids in the body, and mixtures of the salts are useful in the treatment of renal and hepatic disorders characterized by protein intolerance leading to deficiencies of various essential and semi-essential amino acids in the body. They may also be useful in the treatment of nitrogen wasting disorders and protein malnutrition. The novel compounds are generally far more palatable and soluble in aqueous solutions than the individual essential or semi-essential amino acids, nitrogen-free analogues thereof, or simple mixtures of these.
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