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EFFECT OF HUMAN TUMOR NECROSIS FACTOR AND HUMAN INTERFERON ON HUMAN CANCER CELLS AND METHODS
EFFECT OF HUMAN TUMOR NECROSIS FACTOR AND HUMAN INTERFERON ON HUMAN CANCER CELLS AND METHODS
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机译:人肿瘤坏死因子和人干扰素对人癌细胞的影响及方法
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摘要
A method for the production and purification of human tumor necrosis factor (hTNF) is described. This purified material, shows growth inhibitory, hemorrhagic necrosis, cytotoxicity, and cytostasis effects on a variety of human tumors and cancers. The hTNF is free of exogeneous endotoxin, bacteria, and serum factors, hTNF has a molecular weight of about 70,000 hTNF and human interferon used together have a far greater growth inhibitory or cytotoxic effect on human tumors than the sum of their separate effects. The effect is synergistic and is seen with alpha-, beta- or gamma-IFN and with natural and recombinant IFN.
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