a molecule cdna coding for the expression of an interferon alpha type polypeptide, a bacterial or cellular host transformed with such molecule and a polypeptide showing interferon activity prepared by such host

摘要

A cDNA molecule having the nucleotide sequence ( alpha -88) (I) or sequences which hybridize to the foregoing sequence and which code for the expression of a polypeptide of the IFN- alpha type; or sequences which are degenerate as a result of the genetic code to the nucleotide sequence defined above and which code for the expression of a polypeptide of the IFN- alpha type; a bacterial or cellular host transformed with such molecule; a polypeptide having alpha -type interfering activity prepared by such host; and method of therapeutical treatment.