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Process for the preparation of New Derivatives of acids apovincaminicos Racemic and optically Active, and their acid Addition salts
Process for the preparation of New Derivatives of acids apovincaminicos Racemic and optically Active, and their acid Addition salts
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机译:制备外消旋和旋光酸载脂蛋白迷迭香酸新衍生物及其酸加成盐的方法
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摘要
Process for the preparation of New Derivatives of acids apovincaminicos Racemic and optically Active, and their acid Addition Salts.Apovincamino consists on making a Derivative of formula (ii) or an Acid Addition Salt thereof with a monoalquileter Derivative of formula (iii) in the presence of a catalytic amount of an alkali metal monoglicolato derivative Compound of formula (iii), to obtain New deriv Two of apovincaminicos Racemic and optically Active acids of formula (i),Where a is a Group - or - or N - (CH2); R is an alkyl group with 1 to 6 C; n is 2 to 6; R is a group alquilico with C 1 to 6; and Hydrogen in position 3 and the group has R Configuration Bab BAB and / or BBB BBB or Bab, BBB and / or BBB, bab.tiene Application for its activity and be powerful vasodilata antihipoxial Peripheral workers.
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