A blood accelerator 2, 3-diphosphoglyceric acid

摘要

A blood 2,3-diphosphoglyceric acid accelerator which comprises as active ingredients thereof alpha-naphthoquinones or beta-naphthoquinones represented by the following general formula (1):wherein R_I represents a hydrogen atom, halogen atom, lower alkyl group or sulfon group, R₂ represents a hydrogen atom, halogen atom or hydroxycarbonylethylthio group, and the dotted line indicates a double bond at either position of 2 and 3 or 3 and 4.;The alpha- and beta-naphthoquinones elevate the concentration of flood 2,3-DPG which functions to increase the oxygen supply to the issue.;The accelerator agent according to the invention is especially usable for patients in a condition of decreasing 2,3-DPG, for example, after surgical operations or at the time of blood transfusion and for patients suffering from ischemis diseases.