The method of Didier Heathrow milbe erythromycin derivatives

摘要

5-Didehydro milbemycin-5-oxime derivs. of formula (I) are new. In (1), R1 is methyl, ethyl or isopropyl; R2 is H, C1-6 alkyl, aralkyl (opt. substd. by C1-6 alkyl, halogen or NO2) or -CH2COOR3; R3 is H or C1-6 alkyl. Compds. (I) are anthelmintics, acaricides and insecticides. In plants, (I) have a systemic action as well as a contact action against insects.