Preparation of 3-alkoxy-2-(N-pyrrolidino)-N-pyridyl-N-furylmethyl (or furylthienyl)-propylamine

摘要

New Method for preparing 3 - (N - 2 - alkoxy - pyrrolidin-3-yl - pyridyl) - N - N - furilmetil - propilaminas.Comprises: a) reacting a compound of formula (iv) with aminopiridina, in the presence of an alkali metal metalizante - Agent (Sodium HYDRIDE) to produce a compound of formula (ii); and (b) (ii) treated with an Amine of formula (iii),To obtain New 3 - 2 - alkoxy - (N - pirrolidino - pyridyl) - N - N - furilmetil propilaminas of formula (i) and the pharmaceutically acceptable acid Addition Salts. Where: R, linear or branched alkyl C 1 to 7; Hal, cl or BR, and X, o or S. antianginal agents are used as anti hypertensive and anti diarritmicos.