首页> 外国专利> (Nle (arrow high) 8 (arrow high), nle (arrow high) 1 (arrow high) (arrow high) 8 (arrow high), tyr (arrow high) 3 (arrow high) (arrow high) 4 (arrow high)) - h - tph (1 - 34) nh (arrow down) 2 (arrow down) - a peptide derivative

(Nle (arrow high) 8 (arrow high), nle (arrow high) 1 (arrow high) (arrow high) 8 (arrow high), tyr (arrow high) 3 (arrow high) (arrow high) 4 (arrow high)) - h - tph (1 - 34) nh (arrow down) 2 (arrow down) - a peptide derivative

机译:(Nle(箭头高)8(箭头高),Nle(箭头高)1(箭头高)(箭头高)8(箭头高),tyr(箭头高)3(箭头高)(箭头高)4(箭头高))-h-tph(1-34)nh(向下箭头)2(向下箭头)-肽衍生物

摘要

The invention relates to new peptide derivatives parathyroid human hormone (pth h -). More particularly, the invention relates to nle, nle, tyr - h - pth (1 - 34) nh and nle, nle - h - pth (1 - 34) nh which are of the medicinal products are effective for the treatment of diseases involving the hypoparathyroidism or pth. / p & & p & of feature, the peptide answer has the formula: h - ser - val - ser - glu - ile - gln - leu - nle - his - asn - leu - gly - lys - his - leu - asn - ser - nle - glu - arg - val - glu - trp - leu - arg - lys - lys - leu - gln -) - val - his - asn - to - nh, in which a denotes tyr or phe, or a salt of that -.
机译:本发明涉及新的肽衍生物甲状旁腺人激素(pth h-)。更具体地,本发明涉及药物的nle,nle,tyr-h-pth(1-34)nh和nle,nle-h-pth(1-34)nh有效用于治疗涉及以下疾病的药物甲状旁腺功能减退或甲状旁腺功能减退。 & &根据功能,肽的答案具有以下公式:h-ser-val-ser-glu-ile-gln-leu-nle-his-asn-leu-gly-lys-his-leu-asn-ser-nle-glu- arg-val-glu-trp-leu-arg-lys-lys-leu-gln-)-val-his-asn-to -nh,其中a表示tyr或phe,或该盐的盐-。

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