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Process for the disposal of the group of n - formyl of peptides n - formylated and esters of peptides n - formylated
Process for the disposal of the group of n - formyl of peptides n - formylated and esters of peptides n - formylated
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机译:处理n-甲酰化肽的n-甲酰基和n-甲酰化的肽的酯的方法
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摘要
A process for the removal of the formyl group in N-formylated peptides or their esters is described. The N-formyl compound is reacted with hydrazine or a substituted hydrazine of formula I: IMAGE at a pH between 1 and 3.5, keeping the pH constant during the reaction. The process is particularly useful for the preparation of aspartam.
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