HCMV MONOCLONAL ANTIBODIES AND THEIR USE IN THE DETECTION OF HCMV INFECTION AND HCMV SPECIFIC IGM, AND METHODS OF DETECTING VIRAL ANTIGENS

摘要

Monoclonal antibodies reactive to immediate early and/or early HCMV. The detection of antigens (especially HCMV antigens) by concentrating them on a support and reacting them with monoclonal antibody. The support may be a nitrocellulose membrane (immunodot). Alternatively the support may be a bead carrying a different monoclonal antibody, the two antibodies reacting with different epitopic sites on the antigenic protein. The use of HCMV monoclonal antibody in distinguishing between HCMV-specific IgM and IgG.