METHOD FOR TREATMENT OR PREVENTION OF ATHEROSCLEROTIC DISORDERS AND/OR CORONARY HEART DISEASE

摘要

This invention concerns the use in the treatment or prevention of atherosclerotic disorders and/or coronary heart disease of compounds of formula IMAGE IMAGE represents a ring system of formula IMAGE IMAGE wherein R1 represents hydrogen, methyl or benzyl, R2 represents hydrogen or methyl, R3 represents hydrogen or methoxy, R5 represents phenyl, 3-indolyl, 2-furyl, diphenylmethyl, benzyloxy, or phenyl monosubstituted by chlorine, bromine, lower alkyl, carboxy, methylenedioxy, trifluoromethyl or phenyl, or represents phenyl substituted up to three times by lower alkoxy, A represents an ethylene or a 1-oxoethylene biradical, and Z is an oxo- group or, when A is ethylene and R5 is phenyl, may also represent two hydrogen atoms, and X is an anion of a pharmaceutically acceptable acid.