Hybridoma cells secreting a monoclonal antibody specific for 5- bromo and 5-iodoeoxyuridine and reagents for measuring cellular proliferation

摘要

Cells synthesizing DNA are detected in a rapid, non- radioactive assay using the monoclonal antibody reagent secreted by the hybridoma produced in accordance with the present invention. The assay is used to study DNA repair in cells that have been exposed to various environmental toxins, chemotherapeutic agents, and the like. The monoclonal antibody secreted by the hybridoma is a valuable reagent for research and diagnosis.