Production of glucose dehydrogenase and use of the resultant enzyme in the enzymatic synthesis of L-carnitine

摘要

A process for producing glucose dehydrogenase consists of cultivating a mutant strain (ATCC 39 118) of Bacillus megaterium in a culture medium and recovering the resultant glucose dehydrogenase. The latter can be used in the enzymatic production of L-carnitine consisting of subjecting 3-dehydrocarnitine to the simultaneous action of carnitine dehydrogenase, nicotinamide adenine dinucleotide and glucose and glucose dehydrogenase.