CONTINUOUS SYNTHESIS AND APPARATUS FOR ALPHA-AMINO ACID BY CHEMICALLY CATALYTIC HYDROLYSIS

摘要

The device for carrying out the continuous process for synthesizing an alpha -amino acid incorporates: (a) a vessel (10) for feeding alpha -amino-nitrile, or one of its salts; (b) a connecting pipe (12), in which a pump (14) is mounted, connecting the feed vessel (10) to (c) a catalysis column (16) containing a carbonyl-containing polymeric resin (18) which is insoluble in basic aqueous medium; (d) a connecting pipe (20) from the catalysis column (16) to (e) a hydrolysis reactor (22), acting simultaneously as a reservoir for the alpha -amino acid salt formed, and equipped with (f) means for feeding hydroxide ions, comprising a feed vessel (24), a pipe (26) and a pump (28); and (g) a pipe (30) for drawing off the alpha -amino acid salt formed.