Tripeptide derivatives as well as salts thereof with mineral or organic acids for use as substrates for the quantitative determination of the thrombin and thrombin-like enzymes, ecarinthrombin, plasmin and plasmin-like enzymes and proenzymes, enzyme inhibitors and proenzymaktivatorer legemsvaeskerfra this in humans and mammals as well as in animal cell extracts

摘要

A substrate for the quantitative determination of enzymes in human and mammal body fluids as well as in animal cell extracts and glandular venoms of cold-blooded animals, which has the structure R1 - Gly - Pro - X - NH - R2 wherein R1 represents hydrogen or a blocking acyl or sulfonyl group, R2 represents an aromatic hydrocarbon group which may carry substituents and X represents arginyl or lysyl, -NH-R2 being a chromogenic or fluorescent group capable of yielding a split product NH2-R2 the quantity of which can be measured by photometric, spectrophotometric or fluorescence-photometric methods.